NIHR BioResource Supported Studies – national team
Study Number | Study Type | Short Title | Speciality Area | Lead Researcher | Institution or Company |
---|---|---|---|---|---|
NBR 01 | Samples / Data | Affymetrix high-density array NIHR BioResource | Cross-cutting | Prof. John Bradley | University of Cambridge |
NBR 03 | Samples / Data | Metabalon - Mapping metabolites to their key biochemical pathways | Cross-cutting | Prof. John Bradley | University of Cambridge |
NBR 04 | Samples / Data | Cholesterol efflux pathways in monocytes and the genetic risk of atherosclerosis | Cardiovascular | Prof. Martin Bennett | University of Cambridge |
NBR 05 | Volunteer Recall | Investigating changes in memory and attention associated with ageing | Neurological disorders | Prof. Anne Nobre | University of Oxford |
NBR 06 | Volunteer Recall | Inception - Individuals under investigation for possible IBD or newly diagnosed with IBD | Gastroenterology | Dr Miles Parkes | University of Cambridge |
NBR 07 | Samples / Data | Validation of genome-wide and targeted genotyping arrays to enable the ascertainment of blood groups of man to a clinical standard | Haematology | Prof. Willem Ouwehand | University of Cambridge |
NBR 08 | Volunteer Recall | Defining the mechanisms and control of human regulatory T cell function in autoimmunity | Gastroenterology | Prof. Graham Lord | King’s College London |
NBR 09 | Volunteer Recall | Determining an important functional role for integrins in regulating immune responses in IBD | Gastroenterology | Prof. Mark Travis | University of Manchester |
NBR 10 | Volunteer Recall | ApoE and gender: Investigation of short-term memory using the Oxford Memory Task app | Neurological disorders | Prof. Masud Husain | University of Oxford |
NBR 11 | Samples / Data | Progressing from genetics to function and clinical translation in Crohn’s disease & ulcerative colitis | Gastroenterology | Dr Miles Parkes | University of Cambridge |
NBR 12 | Volunteer Recall | GEM – Genetic, environmental, microbial project | Gastroenterology | Dr Miles Parkes | University of Cambridge |
NBR 13 | Samples / Data | Genome-wide association studies of circulating blood metabolites | Haematology | Prof. Tim Spector | University of Cambridge |
NBR 14 | Samples / Data | Discovery of metabolite biomarkers in rare diseases | Rare diseases | Dr Leonardo Bottolo | University of Cambridge |
NBR 16 | Volunteer Recall | The PREdiCCt (The PRognostic effect of Environmental factors in Crohn’s and Colitis) Study | Gastroenterology | Dr Charlie Lees | University of Edinburgh |
NBR 17 | Samples / Data | Impute - 50K imputation at Sanger | Cross-cutting | Dr Jyoti Khadake | University of Cambridge |
NBR 18 | Volunteer Recall | Genetics and metagenome studies in orofacial granulomatosis | Gastroenterology | Dr Natalie Prescott | King’s College London |
NBR 20 | Samples / Data | PANTS - Genetics of immunogenicity to anti-TNF drugs | Gastroenterology | Dr Tariq Ahmed | University of Exeter |
NBR 21 | Volunteer Recall | Mechanism linking NOD2 with MHC class I antigen presentation | Gastroenterology | Prof. Alison Simmons | University of Oxford |
NBR 22 | Samples / Data | CMV infection in inflammatory bowel disease | Gastroenterology | Prof. Holm Uhlig | University of Oxford |
NBR 23 | Volunteer Recall | The genetic correlates of cognitive flexibility and their links to ideological thinking | Neurological disorders | Prof. Trevor Robbins | University of Cambridge |
NBR 24 | Volunteer Recall | Investigation of genetic susceptibility markers to arthritic conditions and how they contribute to disease | Arthritis | Dr Annie Yarwood | University of Manchester |
NBR 25 | Volunteer Recall | Generation of pluripotent stem cell lines to test novel compounds for the treatment of disease | Ophthalmology | Dr David Bunton | REPROCELL Europe Ltd. |
NBR 26 | Volunteer Recall | Cellular investigation of the role of the GMP reductase in haemoglobin metabolism and red blood cell development | Cardiovascular | Dr Dirk Paul | University of Cambridge |
NBR 28 | Volunteer Recall | Crohn’s Anal Fistula Quality of Life Scale | Gastroenterology | Dr Alisa Hart | London NW Healthcare NHS Trust |
NBR 29 | Samples / Data | Assessing whole genome sequencing as a diagnostic test for mitochondrial disease. | Genetics | Prof. Patrick Chinnery | University of Cambridge |
NBR 32 | Samples / Data | Genotype and Phenotype in Inherited Neurodegenerative Diseases | Neurological disorders | Prof. Patrick Chinnery | University of Cambridge |
NBR 33 | Volunteer Recall | NOVID - Role of DNA non-coding variants in von Willebrand disease | Genetics | Prof. Patrick Chinnery | University of Cambridge |
NBR 34 | Volunteer Recall | IBD-Boost Survey: fatigue pain and urgency in IBD | Gastroenterology | Prof. Christine Norton | King’s College London |
NBR 35 | Volunteer Recall | Pulmonary Arterial Hypertension Associated ATP13A3 Mutations | Cardiovascular | Prof. Nick Morrell | University of Cambridge |
NBR 36 | Volunteer Recall | VarClot - Effect of DNA non-coding variants in the MYH9 gene region in the regulation of blood clotting. | Haematology | Dr Mattia Frontini | University of Cambridge |
NBR 37 | Volunteer Recall | AdipO2 - Body fat distribution and diabetes risk: the role of adipose tissue oxygen metabolism | Metabolism | Dr Konstantinos Manolopoulos | University of Birmingham |
NBR 38 | Samples / Data | Understanding contributions of T cell determining factors in the pathogenesis of IBD | Gastroenterology | Prof. Adrian Hayday | King’s College London |
NBR 39 | Volunteer Recall | ROVIM - Role of blood group VEL in metabolism. | Metabolism | Dr Mattia Frontini | University of Cambridge |
NBR 40 | Volunteer Recall | IBD Risk Alleles - Effect of genetic variants associated with risk for inflammatory disease on immune cell phenotype and function. | Gastroenterology | Dr Carl Anderson | Wellcome Sanger Institute |
NBR 41 | Volunteer Recall | ROTEC - Inherited changes leading to altered levels of a blood protein, tissue factor pathway inhibitor and risk of cardiovascular disease | Haematology | Dr William Astle | University of Cambridge |