BioResource Support

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  • Data
    • Data Overview
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  • Applications
    • Application process
    • Approved studies
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    • Acknowledging the BioResource
  • Publications
    • Publications

Approved studies

NIHR BioResource Supported Studies – national team

Study NumberStudy TypeShort TitleSpeciality AreaLead ResearcherInstitution or Company
NBR 01Samples / DataAffymetrix high-density array NIHR BioResourceCross-cuttingProf. John BradleyUniversity of Cambridge
NBR 03Samples / DataMetabalon - Mapping metabolites to their key biochemical pathwaysCross-cuttingProf. John BradleyUniversity of Cambridge
NBR 04Samples / DataCholesterol efflux pathways in monocytes and the genetic risk of atherosclerosisCardiovascularProf. Martin BennettUniversity of Cambridge
NBR 05Volunteer RecallInvestigating changes in memory and attention associated with ageingNeurological disordersProf. Anne NobreUniversity of Oxford
NBR 06Volunteer RecallInception - Individuals under investigation for possible IBD or newly diagnosed with IBDGastroenterologyDr Miles ParkesUniversity of Cambridge
NBR 07Samples / DataValidation of genome-wide and targeted genotyping arrays to enable the ascertainment of blood groups of man to a clinical standardHaematologyProf. Willem OuwehandUniversity of Cambridge
NBR 08Volunteer RecallDefining the mechanisms and control of human regulatory T cell function in autoimmunityGastroenterologyProf. Graham LordKing’s College London
NBR 09Volunteer RecallDetermining an important functional role for integrins in regulating immune responses in IBDGastroenterologyProf. Mark TravisUniversity of Manchester
NBR 10Volunteer RecallApoE and gender: Investigation of short-term memory using the Oxford Memory Task appNeurological disordersProf. Masud HusainUniversity of Oxford
NBR 11Samples / DataProgressing from genetics to function and clinical translation in Crohn’s disease & ulcerative colitisGastroenterologyDr Miles ParkesUniversity of Cambridge
NBR 12Volunteer RecallGEM – Genetic, environmental, microbial projectGastroenterologyDr Miles ParkesUniversity of Cambridge
NBR 13Samples / DataGenome-wide association studies of circulating blood metabolites
HaematologyProf. Tim SpectorUniversity of Cambridge
NBR 14Samples / DataDiscovery of metabolite biomarkers in rare diseasesRare diseasesDr Leonardo BottoloUniversity of Cambridge
NBR 16Volunteer RecallThe PREdiCCt (The PRognostic effect of Environmental factors in Crohn’s and Colitis) StudyGastroenterologyDr Charlie LeesUniversity of Edinburgh
NBR 17Samples / DataImpute - 50K imputation at SangerCross-cuttingDr Jyoti KhadakeUniversity of Cambridge
NBR 18Volunteer RecallGenetics and metagenome studies in orofacial granulomatosisGastroenterologyDr Natalie PrescottKing’s College London
NBR 20Samples / DataPANTS - Genetics of immunogenicity to anti-TNF drugsGastroenterologyDr Tariq AhmedUniversity of Exeter
NBR 21Volunteer RecallMechanism linking NOD2 with MHC class I antigen presentationGastroenterologyProf. Alison SimmonsUniversity of Oxford
NBR 22Samples / DataCMV infection in inflammatory bowel diseaseGastroenterologyProf. Holm UhligUniversity of Oxford
NBR 23Volunteer RecallThe genetic correlates of cognitive flexibility and their links to ideological thinkingNeurological disordersProf. Trevor RobbinsUniversity of Cambridge
NBR 24Volunteer RecallInvestigation of genetic susceptibility markers to arthritic conditions and how they contribute to diseaseArthritisDr Annie YarwoodUniversity of Manchester
NBR 25Volunteer RecallGeneration of pluripotent stem cell lines to test novel compounds for the treatment of diseaseOphthalmologyDr David BuntonREPROCELL Europe Ltd.
NBR 26Volunteer RecallCellular investigation of the role of the GMP reductase in haemoglobin metabolism and red blood cell developmentCardiovascularDr Dirk PaulUniversity of Cambridge
NBR 28Volunteer RecallCrohn’s Anal Fistula Quality of Life ScaleGastroenterologyDr Alisa HartLondon NW Healthcare NHS Trust
NBR 29Samples / DataAssessing whole genome sequencing as a diagnostic test for mitochondrial disease.GeneticsProf. Patrick ChinneryUniversity of Cambridge
NBR 32Samples / DataGenotype and Phenotype in Inherited Neurodegenerative DiseasesNeurological disordersProf. Patrick ChinneryUniversity of Cambridge
NBR 33Volunteer RecallNOVID - Role of DNA non-coding variants in von Willebrand diseaseGeneticsProf. Patrick ChinneryUniversity of Cambridge
NBR 34Volunteer RecallIBD-Boost Survey: fatigue pain and urgency in IBDGastroenterologyProf. Christine NortonKing’s College London
NBR 35Volunteer RecallPulmonary Arterial Hypertension Associated ATP13A3 MutationsCardiovascularProf. Nick MorrellUniversity of Cambridge
NBR 36Volunteer RecallVarClot - Effect of DNA non-coding variants in the MYH9 gene region in the regulation of blood clotting.HaematologyDr Mattia FrontiniUniversity of Cambridge
NBR 37Volunteer RecallAdipO2 - Body fat distribution and diabetes risk: the role of adipose tissue oxygen metabolismMetabolismDr Konstantinos ManolopoulosUniversity of Birmingham
NBR 38Samples / DataUnderstanding contributions of T cell determining factors in the pathogenesis of IBDGastroenterologyProf. Adrian HaydayKing’s College London
NBR 39Volunteer RecallROVIM - Role of blood group VEL in metabolism.MetabolismDr Mattia FrontiniUniversity of Cambridge
NBR 40Volunteer RecallIBD Risk Alleles - Effect of genetic variants associated with risk for inflammatory disease on immune cell phenotype and function.GastroenterologyDr Carl AndersonWellcome Sanger Institute
NBR 41Volunteer RecallROTEC - Inherited changes leading to altered levels of a blood protein, tissue factor pathway inhibitor and risk of cardiovascular diseaseHaematologyDr William AstleUniversity of Cambridge

Application process

Approved studies

Approved Data Access Agreements

Visit us

NIHR National BioResource for Translational Research in Common and Rare Diseases
Coton House, Level 5
Cambridge Biomedical Campus
Hills Road
Cambridge
CB2 0QQ

NIHR BioResource Central Team

University of Cambridge and Cambridge University Hospital NHS Foundation Trust
Box 299
Cambridge Biomedical Campus
Hills Road
Cambridge
CB2 0QQ

Contact us

General enquiries email: nbr@bioresource.nihr.ac.uk freephone number: 0800 090 2233.  Accessibility statement. Website:   bioresource.nihr.ac.uk

NIHR BioResource

https://www.youtube.com/watch?v=BR0mvJh7Cxk

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